-
Venlafaxine CAS: 93413-69-5
Venlafaxine jẹ apakokoro ti serotonin ati norẹpinẹpirini reuptake inhibitor (SNRI) kilasi.Oogun yii jẹ idagbasoke akọkọ nipasẹ Wyeth ni 19Chemicalbook93 ati pe o jẹ tita nipasẹ Pfizer.Oogun yii jẹ itẹwọgba fun itọju ailera aibalẹ nla (MDD), rudurudu aifọkanbalẹ gbogbogbo (GAD), ati ibanujẹ ti o ni nkan ṣe pẹlu aibalẹ.
-
β-Nicotinamide Mononucleotide CAS: 1094-61-7
Nicotinamide mononucleotide (NMN), ọja ti iṣesi NAMPT ati agbedemeji NAD + bọtini kan, ṣe imudara ailagbara glukosi nipasẹ mimu-pada sipo awọn ipele NAD + ninu awọn eku T2D ti o fa HFD.NMN tun ṣe alekun ifamọ hisulini ẹdọ ati mimu-pada sipo ikosile jiini ti o ni ibatan si aapọn oxidative, idahun iredodo, ati rhythm ti circadian, ni apakan nipasẹ imuṣiṣẹ SIRT1.NMN ni a lo fun kikọ ẹkọ awọn idii abuda laarin awọn aptamers RNA ati awọn ilana imuṣiṣẹ ribozyme ti o kan β-nicotinamide mononucleotide (β-NMN) -awọn ajẹkù RNA ti mu ṣiṣẹ.
-
β-Nicotinamide Adenine Dinucleotide CAS: 53-84-9
β-Nicotinamide adenine dinucleotide (NAD) jẹ fọọmu oxidized ti β-Nicotinamide Adenine Dinucleotide.O wa bi anion labẹ awọn ipo physio-logic deede.O jẹ ibatan si iṣẹ ṣiṣe si deamido-NAD zwitterion.O jẹ ipilẹ conjugate ti NAD (+).O wa ni ibigbogbo ni iseda ati pe o ni ipa ninu ọpọlọpọ awọn aati enzymatic ninu eyiti o ṣe iranṣẹ bi agbẹru elekitironi nipasẹ jijẹ oxidized omiiran (NAD +) ati dinku (NADH).
-
β-Nicotinamide Adenine Dinucleotide, fọọmu ti o dinku CAS: 606-68-8
β-Nicotinamide adenine dinucleotide (NAD +) ati β-Nicotinamide adenine dinucleotide, ti o dinku (NADH) ni ninu bata coenzyme redox (NAD +: NADH) ti o ni ipa ninu titobi pupọ ti enzymu catalyzed oxidation idinku awọn aati.Ni afikun si iṣẹ redox rẹ, NAD +/NADH jẹ oluranlọwọ ti awọn ẹya ADP-ribose ni ADP-ribosylaton (ADP-ribosyltransferases; poly (ADP-ribose) polymerases) awọn aati ati ipilẹṣẹ ti ADP-ribose cyclic (ADP-ribosyl cyclases) .
-
β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Iyọ, fọọmu ti o dinku CAS: 2646-71-1
NADPH jẹ fọọmu ti o dinku ti coenzyme NADP +;ti a lo ninu awọn aati anabolic gẹgẹbi iṣelọpọ lipid ati nucleic acid, eyiti o nilo NADPH gẹgẹbi oluranlowo idinku.NADPH, Iyọ Tetrasodium jẹ coenzyme kan ti o wa ni gbogbo ibi ti o ṣe bi oluranlọwọ elekitironi ni ọpọlọpọ awọn aati ti o nlo dehydrogenase ati awọn enzymu reductase.O jẹ ipilẹṣẹ nipasẹ idinku ti olugba itanna NADP+.Awọn ipa ọna isedale atẹle pẹlu NADPH: dida carbohydrate lati CO2 lakoko photosynthesis, itọju awọn ipele giga ti glutathione ti o dinku ni awọn erythrocytes, idinku ti thioredoxin.
-
Thio-Nicotinamide Adenine Dinucleotide (Thio-NAD) CAS: 4090-29-3
Thionicotinamide adenine dinucleotide jẹ afọwọṣe ti NAD.Lilo Thio-NAD dipo NAD bi sobusitireti fun NAD (+) -awọn enzymu jijẹ jẹ anfani diẹ sii nitori ọna ti o dinku ti Thio-NAD ṣe afihan ilosoke pupọ ninu gbigba ni 405 nM, gigun gigun ti o wọpọ julọ lori awọn oluka microplate.
-
β-Nicotinamide Adenine Dinucleotide Phosphate Monosodium Iyọ CAS: 1184-16-3
Nicotinamide adenine dinucleotide fosifeti, abbreviated NADP + tabi, ni akọsilẹ agbalagba, TPN (triphosphopyridine nucleotide), jẹ cofactor ti a lo ninu awọn aati anabolic, gẹgẹ bi ọmọ Calvin ati lipid ati nucleic acid syntheses, eyiti o nilo NADPH gẹgẹbi oluranlowo idinku ('orisun hydrogen). ') .O ti wa ni lilo nipasẹ gbogbo iwa ti cellular aye.
-
Ciclopirox Ethanolamine CAS: 41621-49-2 Olupese Olupese
Ciclopirox ethanolamine jẹ oluranlowo antigfungal ti o gbooro, o tun ṣe afihan iṣẹ-ṣiṣe antibacterial lodi si ọpọlọpọ awọn kokoro arun Gram-positive ati Gram-negative, o si ni awọn ohun-ini egboogi-iredodo.O ti wa ni lilo aa ti agbegbe itoju ti olu ara ẹya àlàfo àkóràn.
-
Desvenlafaxine Succinate CAS: 386750-22-7
Desvenlafaxine Succinate jẹ serotonin meji ati norẹpinẹpirini reuptake inhibitor (SNRI) ti a fọwọsi fun itọju ailera aibanujẹ nla (MDD) ni Amẹrika ni 2008. Lati mu ilọsiwaju ati profaili ailewu ti venlafaxine, Wyeth ṣe awari ati idagbasoke ọkan. ti awọn metabolites pataki ti venlafaxine, eyun O-desmethyl metabolite (desvenlafaxine).
-
Doxazosin Mesylate CAS: 77883-43-3 Olupese Olupese
Doxazosin mesylate jẹ agbo-ara quinazoline ti o jẹ oludaniloju yiyan ti alpha1 subtype ti awọn olugba alpha adrenergic.Doxazosin mesylate jẹ iran tuntun ti quinazolone α1 receptor blocker ti o ni idagbasoke nipasẹ ile-iṣẹ Pfizer (United States), O ni igbesi aye idaji pipẹ, ti n ṣiṣẹ awọn ipa rẹ ti dilating awọn ohun elo ẹjẹ, dinku resistance iṣọn-ẹjẹ ati sisọ titẹ ẹjẹ silẹ nipasẹ didi a 1 olugba.O ti ṣe iṣeduro ni okeere bi awọn oogun ile-iwosan akọkọ-akọkọ ti egboogi-haipatensonu ati itọju ti arun pirositeti.
-
L-Isoleucine CAS: 73-32-5 Olupese Olupese
L-Isoleucine, ti a tun mọ ni Isoleucine, jẹ amino acid ti o jẹ isomer ti leucine.O ṣe pataki ni iṣelọpọ hemoglobin ati ilana ti suga ẹjẹ ati awọn ipele agbara.L-Isoleucine jẹ isomer ti L-leucine ati pe o jẹ amino acid pataki.O ti wa ni sise lati threonine ati ki o jẹ a branched-pq hydrophobic amino acid.
-
Captopril CAS: 62571-86-2 Olupese Olupese
Captopril jẹ iwadi ti o pọ julọ ti awọn inhibitors enzymu iyipada angiotensin ti a dabaa bi oogun antihypertensive.O ṣe idiwọ henensiamu iyipada angiotensin, eyiti o dinku idasile ti angiotensin II ati mu ipa vasoconstricting rẹ silẹ lori awọn ohun elo iṣọn-ẹjẹ ati iṣọn-ẹjẹ.Lapapọ ẹdọfu agbeegbe ti iṣan ti dinku, eyiti o yorisi idinku ti titẹ iṣan.
